Sichuan Xincheng SARS-CoV-2 Antigen Assay

Description

According to scientific studies, multiple detection methods should be applied together to complement with each other when detecting SARS-Cov-2. Researchers found that combining molecular nucleic acid test and immune level detection can be of many advantages: improve sensitivity and specificity, shorten the detection window period, improve the positive detection rate, identify course of disease, increase flexibility and accessibility to POCT testing and medical resources, and provide double protection for all possible risk groups.

In one publication on Cell Death Discovery of Nature, our antibody test by immunofluorescence chromatography method is highly rated and recommended to be tested jointly with nucleic acid test (PCR test) for comprehensive detection.

Antigen test can be used as a supplementary test indicator for suspected cases with negative nucleic acid test of SARS-Cov-2 or used in conjunction with nucleic acid testing in the diagnosis of suspected cases.

XinCheng Bio SARS-Cov-2 Antigen Assay Kit by Latex Immunochromatography Method

Strengths and Highlights

1. Rapid POCT
   • Our CE marked in vitro diagnostic kits can be used directly at the point of care testing (POCT)
   • Test result shows in just 15 minutes
2. Easy to Operate
   • No lab setting is required for operation
   • No instrument or analyzer is needed
3. Multiple Accurate
   • The test gives qualitative result also on Influenza A and B antigens
   • Highly accurate: independent clinical trials show a precision of more than 80%
4. Cost-Efficient
   • The cost is much less than nucleic acid test (PCR) with expensive labs
   • The test kit is lightweight and small in dimension, thus freight and handling cost is low

Test Principle: Latex immunochromatography method is used to detect SARS-Cov-2, influenza A or influenza B virus antigens. After treatment when SARS-Cov-2, influenza A or B virus antigens in the sample are added to the detection hole, the antigen and latex labeled antibody (monoclonal antibody against SARS-Cov-2, influenza A or B antigen) form an immune complex. The complex moves with the liquid to the nitrocellulose membrane, and the detection area of the nitrocellulose membrane is coated with another one.

Test Result: When monoclonal antibody is against SARS-Cov-2, influenza A or B antigen, the immune complex is captured by the antibody on nitrocellulose membrane, forming a red reaction line: the result is positive. When the sample does not contain SARS-Cov-2 antigen, influenza A or B antigens or are lower than the minimum detection limit of this kit, no red reaction line appears in the detection area: the result is negative. At the same time, whether the result is positive or negative, as the internal control standard of reagents, a red reaction line will be formed in the quality control area (line C), which is used to judge whether the chromatographic process is normal or not.